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Some people spend a lifetime trying to amass a fortune through hard work and guile. For one British man, it took only 20 minutes in a field with a metal detector — the first 20 minutes he had ever used such a machine.

According to the St. Albans & Harpenden Review, Wesley Carrington took his newly bought metal detector out into a field near St. Albans in Hertfordshire, England, last October. After finding a spoon and then a half penny, Carrington’s machine beeped a third time, and he dug seven inches down to uncover a coin that was gold in color with a Roman figure on it.

As it turns out, the gold coloring was actually gold, the coin was an ancient Roman solidus, and there were 158 more buried with it, a hoard with an estimated worth of 100,000 pounds sterling, or $156,000, according to The Daily Mail.

Carrington found 55 of the coins that first night, stopping only because it got too dark outside to continue. A group of experts later returned to discover 104 more coins at the site. All in all, the hoard is believed to be one of the largest collections of Roman gold coins ever found in England, according to the BBC. St. Albans District Councillor Mike Wakely hailed it as “an exciting find of national significance,” the outlet reports.

The statistical likelihood of finding a hoard of such import with so little effort is difficult to calculate, much less grasp.

“I?ve been in the job for ten years and it is certainly the most spectacular find,” Julian Watters, the finds liaison officer for Hertfordshire and Bedfordshire, told The Daily Mail. “Just to put it in context, I had only previously seen four Roman gold coins out of 50,000 finds,” explained Watters, who helped excavate the remaining coins.

Carrington told the St. Albans & Harpenden Review that he did nothing to prepare for his treasure hunt besides watching a few YouTube videos about using a metal detector, and that he chose his location by driving to “the closest area of woodland to where I live.”

Even his metal detector was a beginner’s tool. According to The Daily Mail, Carrington chose his Garrett Ace 150 detector because it was the most basic model at the shop closest to him, in Berkhampstead. A online vendor of metal detectors described the Garrett Ace 150 as “the ideal metal detector for parent-child expeditions or for adults interested in exploring a potential hobby.”

The find was so unlikely that Carrington himself did not initially realize what he had. Days after his discovery, he took a coin back to the Berkhampstead shop and asked what he should do with it, the Daily Express reports. Owner David Sewell recalled being “gobsmacked” by the discovery. “He came to see us and we looked at it and thought: ‘Is this a stunt?'” he said.

Sewell referred Carrington to the local history museum, which organized the larger excavation of the area.

One element of Carrington’s first-time success shouldn’t be a complete surprise: the location. According to the Associated Press, St. Albans lies in an area rich with Roman historical artifacts. The town “boasts a Roman theater and ruins of ancient walls,” and is home to a museum devoted to documenting “everyday life in Roman Britain,” AP notes.

According to The Daily Mail, the coins will now be sent to the British Museum for an official appraisal, after which they will go to auction. Carrington must split the proceeds with the owner of the land where the coins were unearthed.

In the meantime, he has joined a metal detecting club and will continue his treasure hunting in the fields of Hertfordshire. Unfortunately, Carrington says that he hasn’t found anything since October. They don’t call it beginner’s luck for nothing.

Original article on

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One of the best studied hormone-behavior interactions is the transient rise testosterone (T) associated with male-male aggression. However, recent research on songbirds has demonstrated numerous exceptions to this pattern.One species previously thought to elevate T in response to a simulated territorial intrusion is the dark-eyed junco (Junco hyemalis). Here, we show that under most circumstances male juncos do not elevate circulating T or CORT levels in response to social stimuli, despite being physiologically capable of elevating T as indicated by their response to GnRH. The lack of hormonal response was found regardless of the sex of the social stimulus (singing male vs. soliciting female), its sensory modality (song only, song + live lure, song + taxidermic mount), or the timecourse of sampling. Notably, males did elevate T levels when exposed to a simulated territorial intrusion in the days following simulated predation of their chicks. Whether the high T seen in these narrow circumstances represents stage-dependent social modulation of T or re-activation of male reproductive physiology in preparation for re-nesting (i.e. socially independent T modulation) remains to be determined. It is clear, however, that activation of the HPG axis is highly context-specific for male juncos. These results highlight important and unresolved issues regarding the socially mediated component of the challenge hypothesis and how it relates to the evolution of hormone-mediated traits. .

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Cross-sex hormone treatment of transsexual people may be associated with the induction and growth stimulation of hormone-related malignancies. We report here five cases of breast cancer, three in female-to-male (FtoM) transsexual subjects and two in male-to-female (MtoF) transsexual subjects. In the general population the incidence of breast cancer increases with age and with duration of exposure to sex hormones. This pattern was not recognised in these five transsexual subjects. Tumours occurred at a relatively young age (respectively, 48, 41, 41, 52 and 46 years old) and mostly after a relatively short span of time of cross-sex cheap jerseys China hormone treatment (9, 9-10 but in one after 30 years). Occurrence of breast cancer was rare. As has been reported earlier, breast tumours may occur in residual mammary tissue after breast ablation in FtoM transsexual people. For adequate treatment and decisions on further cross-sex hormone treatment it is important to have information on the staging and histology of the breast tumour (type, grade and receptor status), with an upcoming role for the androgen receptor status, especially in FtoM transsexual subjects with breast cancer who receive testosterone administration. This information should be taken into account when considering further cross-sex hormone treatment. .

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To explore the medical and surgical clinical dilemmas in the management of trans (transgender) men, a growing population receiving more attention than in the past. .

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The influence of aging on the HPG axis is sex dependent. The pattern of age-related TT was different in Chinese Han men when compared with previous studies in Western populations. TT values increased in aging men, so it is not suitable to estimate the life quality of older Chinese men just based on TT. .

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The study included 16 untreated women with elevated testosterone levels and 15 matched healthy women who were then treated with oral contraceptive pills containing ethinyl estradiol (30?g) and drospirenone (3mg). Plasma lipids, glucose homeostasis markers, circulating levels of androgens, uric acid, high-sensitivity C-reactive protein (hsCRP), fibrinogen and homocysteine, as well as urinary albumin-to-creatinine ratio (UACR) were assessed at baseline and after 12 weeks of treatment. .

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The aim of this study was to evaluate the effect of overload training on the function of peritoneal macrophages in rats, and to test the hypothesis that glutamine in vivo supplementation would partly reverse the eventual functional alterations induced by overload training in these cells. Forty male Wistar rats were randomly divided into 5 groups: control group (C), overload training group (E1), overload training and restore one week group (E2), glutamine-supplementation group (EG1), and glutamine-supplementation and restore 1-week group (EG2). All rats, except those placed on sedentary control were subjected to 11 weeks of overload training protocol. Blood hemoglobin, serum testosterone, and corticosterone of rats were measured. Moreover, the functions (chemotaxis, phagocytosis, cytokines synthesis, reactive oxygen species generation) of peritoneal macrophages were determined. Data showed that blood hemoglobin, serum testosterone, corticosterone and body VigRx Plus weight in the overload training group decreased significantly as compared with the control group. Meanwhile, the chemotaxis capacity (decreased by 31%, p = .003), the phagocytosis capacity (decreased by 27%, p = .005), the reactive oxygen species (ROS) generation (decreased by 35%, p = .003) and the cytokines response capability of macrophages were inhibited by overload training. However, the hindering of phagocytosis and the cytokines response capability of macrophages induced by overload training could be ameliorated and reversed respectively, by dietary glutamine supplementation. wholesale jerseys These results suggest that overload training impairs the function of peritoneal macrophages, which is essential for the microbicidal actions of macrophages. This may represent a novel mechanism of immunodepression induced by overload training. Nonetheless, dietary glutamine supplementation could partly reverse the impaired macrophage function resulting from overload training. .

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